INTEGRATED INDICATORS OF INTESTINAL LIPOPOLYSACCHARIDE AND ANTIENDOXIVE IMMUNITY BY PATIENTS WITH ATHEROSCLEROSIS OF THE LOWER LIMBS WITH DYSCIRCULATORY ATHEROSCLEROTIC ENCEPHALOPATHY

Chizhikov Nikolay Vasilyevich, Doctor of medical sciences, professor, department of clinical oncology, Medical institute, Penza State Universit, medsekr@pnzgu.ru
Yurevich Elena Vladislavovna, Neurologist, head of neurology unit, Penza regional hospita, penzcrb_post@sura.ru
Oparina Olga Nikolaevna, Doctor of biological sciences, professor, sub-department of physical education theory, Penza State Pedagogical University named after V. G. Belinsky, medsekr@pnzgu.ru
Ageev Ivan Stepanovich, Doctor of medical sciences, professor, head of clinical oncology sub-department, Medical institute, Penza State University, medsekr@pnzgu.ru

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The article presents the results of a research into the condition of the endotoxin-antiendotoxinic system of the patients with concomitant atherosclerotic injury of pelvic limbs and encephalon in accordance with the up-to-date conception of etymology and pathogenesis of atherosclerosis of pelvic limbs. The role of the endotoxin of gram-negative bacteria is shown as a factor initiating formation of atheromas and favouring the progression of the disease. The authors have been first to use the new methods of detection of the content of endotoxin in blood plasma and estimation of the functional condition of humoral and granulocytic parts of antiendotoxinic immunity of the patients with atherosclerosis of pelvic limbs and its complications in the course of different kinds of treatment.

bowel lipopolysaccharide, antiendotoxinic immunity, atherosclerosis of pelvic limbs, encephalopathy